Technology Assessment Reports (TARs)

Technology Assessment Reports are detailed analyses of new pharmaceuticals. They are used to determine the cost-effectiveness of pharmaceuticals that we are being asked to fund.

We don't publish most of our Technology Assessment Reports because of commercial sensitivity. You can download our published reports on this page.

Published Pharmac Technology Assessment Reports

Freestyle Libre flash glucose monitoring system

TAR 417 Economic analysis on the Freestyle Libre flash glucose monitoring system for type 1 diabetes [PDF, 2.2 MB]

Ivacaftor for cystic fibrosis with the G551D mutation

TAR 400 Ivacaftor for cystic fibrosis with the G551D mutation [PDF, 1.3 MB]

Supplementary material for TAR 400 [PDF, 447 KB]

SGLT 2 inhibitors (modelled as empagliflozin)

TAR 382 SGLT 2 inhibitors for type 2 diabetes(external link)

Ustekinumab (Stelara)

TAR 372 ustkinumab for sever crohn's disease [PDF, 4.8 MB]

Eculizumab (Soliris)

TAR 209 Preliminary economic analysis on eculizumab for paroxysmal nocturnal haemoglobinuria (PNH) May 2013 [PDF, 807 KB]

Nusinersen (Spinraza)

TAR 398 Nusinersen for Spinal Muscular Atrophy February 2020 [PDF, 7.4 MB]

Trastuzumab (Herceptin)

TAR 75a,b Trastuzumab (Herceptin) in HER-2 positive early breast cancer with 9 week regimen CUA [PDF, 566 KB]

• Appendix 1 [PDF, 164 KB]
• Appendix 2 [PDF, 125 KB]
• Appendix 3 [PDF, 61 KB]
• Appendix 4 [PDF, 64 KB]
• Appendix 5 [PDF, 178 KB]
• Appendix 6 [PDF, 511 KB]

TAR 75c Tastuzumab further sensitivity analysis [PDF, 401 KB]

• Appendix 7 to TAR 75c [PDF, 260 KB]
• Appendix 8 to TAR 75c [PDF, 373 KB]
• Appendix 9 to TAR 75c [PDF, 64 KB]

Pembrolizumab

TAR 271a and 271b Pembrolizumab in advanced melanoma [PDF, 7 MB]

Other Technology Assessment Reports

Left atrial appendage occlusion devices (LAAO) [PDF, 492 KB]

Dabigatran for the prevention of stroke, systemic embolism and reduction of vascular mortality in patient with atrial fibrilation [PDF, 2.5 MB]

Combined long-acting beta agonist/inhaled corticosteroid devices for asthma (referred to in letter to Journal of Allergy & Clinical Immunology (Metcalfe, Moodie 2003)) [PDF, 76 KB]

Updated statin cost utility analysis [PDF, 120 KB]

• 1997 statin cost utility analysis - methods and assumptions [PDF, 630 KB]
• 1997 statin cost utility analysis - summary of results [PDF, 244 KB]
• 1997 statins for familial hyperlipidaemia [PDF, 238 KB]

Celebrex's relative GI safety is overstated? [PDF, 1.1 MB] A critique and reworking of an industry-sponsored meta-analysis of COX-2 inhibitors (Deeks et al 2002) (sent as a letter to the British Medical Journal, October 2002)

• Further commentary I(external link)
• Further commentary II(external link)
• The original paper(external link)