Pūahoaho: updated information about Pharmac’s priority lists
Pharmac’s quarterly Pūahoaho Report contains the latest information about applications for medicines, vaccines, and related products that we’ve assessed for funding in New Zealand.
It informs the public about current figures and the latest proposals added to the priority lists and gives people certainty about our progress around funding applications.
Proactively releasing this information is part of our ongoing commitment to transparency.
Application priority lists
Every year we receive over 100 funding applications from health care professionals, consumer groups and suppliers. These applications include requests for new medicines and to widen access to medicines that we already fund.
We take these applications to our clinical advisory committees, who use their expertise and assess the available evidence to recommend whether we should fund, defer, or decline them. With their advice, we work to complete an assessment, including a health economic appraisal if required.
We apply the Factors for Consideration throughout our assessment of an application. The factors consider four areas: health need, health benefit, suitability, and costs and savings, which apply to the individual, the family, whānau, society, and the health system.
Once the assessment is complete, we take the application to an internal quarterly prioritisation meeting and add applications to one of three priority lists:
- options for investment (OFI)
- only funded if cost neutral or cost saving
- recommended for decline.
Priority lists for funding applications
Options for investment list
The options for investment list includes applications that we would fund if our budget allowed it. We rank the applications on this list from highest to lowest priority but keep this confidential so we can negotiate the best prices with suppliers.
As of 24 June 2024, there are 147 applications in our options for investment list(external link)
Prioritisation activity in the June quarter
During the June 2024 prioritisation quarter, we ranked 14 proposals on the options for investment list, and re-prioritised 8 others. Re-prioritisation can occur due to more information becoming available, or a change in an application’s Factors for Consideration relative to other funding options.
New proposals ranked (detailed descriptions of indications available on the Application Tracker):
- atogepant(external link), galcanezumab(external link), and erenumab(external link)for chronic migraine
- atogepant(external link), galcanezumab(external link), and erenumab(external link)for episodic migraine
- BTK inhibitors: ibrutinib(external link)and zanubrutinib(external link) for a type of blood cancer called mantle cell lymphoma
- cannabidiol(external link) for a form of epilepsy in children called Dravet syndrome
- migalastat(external link)for a neurological condition called Fabry disease
- pertuzumab IV(external link) for early stage HER2+ breast cancer
- pertuzumab and trastuzumab (PHESGO)(external link) for early stage HER2+ breast cancer
- recombinant zoster (shingles) vaccine(external link) for the prevention of shingles, where people did not receive the vaccine during the COVID-19 pandemic
- spinal muscular atrophy (SMA) treatments: risdiplam and nusinersen(external link) for various types of SMA in people aged 18 years and under
Applications re-ranked:
- agalsidase alfa(external link) for a neurological condition called Fabry disease (a neurological condition that can affect many parts of the body, including the kidneys, heart, and skin)
- budesonide orodispersible tablets(external link) for an immune system disease called eosinophilic oesophagitis
- crizotinib(external link) for a type of lung cancer
- entrectinib(external link) for a type of lung cancer
- letermovir(external link) to prevent a certain viral infection in people receiving a stem cell transplant
- recombinant zoster (shingles) vaccine(external link) to prevent shingles in Māori and Pacific People aged 60 years and over
- recombinant zoster (shingles) vaccine(external link) to prevent shingles in people aged 50 years and a catch up programme for people aged 51–64 years, lowering the age for vaccination
- recombinant zoster (shingles) vaccine(external link) in people aged over 65 years who received the Zostavax brand of the shingles vaccine over five years ago
Only if cost neutral or cost saving list
If our assessment confirms an application does not provide any additional health benefit compared to treatments we already fund, it may be ranked on the only if cost-neutral or cost-saving list. We would look to fund these applications if we negotiated a deal that would be cost-neutral or cost-saving.
Prioritisation activity in the June quarter
During the June 2024 prioritisation quarter, we ranked 6 applications on the only if cost neutral or cost saving list (detailed descriptions of indications available on the Application Tracker):
- cladribine(external link)for relapsing-remitting multiple sclerosis
- ibrutinib(external link)plus venetoclax for a type of blood cancer called chronic lymphocytic leukaemia
- lacosamide oral solution(external link) for epilepsy
- natalizumab (subcutaneous administration)(external link)for relapsing-remitting multiple sclerosis
- pertuzumab with trastuzumab (subcutaneous administration)(external link) for a type of breast cancer
- taurolidine and citrate(external link) to put in a catheter to prevent blocking
Recommended for decline list
There are a range of reasons a funding application may be added to the recommend for decline list. Our expert clinical advisors may have recommended that the funding application be declined, or they may have provided a positive recommendation but we’ve found:
- other more clinically preferred medicines for the same condition are now funded, making the funding application no longer relevant
- the medicine would provide no additional benefits over other treatments we already fund, or may be harmful
- the application has been superseded by another funding application
- no company is supplying the medicine in New Zealand.
When applications are added to this list, they become inactive and we stop progressing work on the application. While applications may be listed on the decline list, they are only formally declined after public consultation to ensure we haven’t missed anything important.
More about this process: Declining inactive funding applications
If we decline an application, it means the medicine would not be funded for the use requested at this time. It does not prevent us from reconsidering funding for the medicine in the future if information becomes available.
Prioritisation activity in the June quarter
During the June 2024 prioritisation quarter, we ranked 19 applications on the recommended for decline list (detailed descriptions of indications available on the Application Tracker):
- alirocumab(external link)to prevent cardiovascular events for people with the genetic disorder heterozygous familial hypercholesterolaemia (HeFH)
- alirocumab(external link)to prevent cardiovascular events for people with diabetes and acute coronary syndrome (ACS)
- aprepitant(external link)to prevent nausea and vomiting associated with use of anti-cancer treatments
- collagenase clostridium histolyticum (XIAFLEX)(external link)for a hand condition called Dupuytren’s contracture
- cyproterone acetate 10mg tablets(external link) for testosterone suppression
- desmopressin(external link) for a rare disorder called arginine vasopressin deficiency
- eribulin(external link)for a type of breast cancer (following progression on chemotherapy)
- esketamine(external link)for treatment resistant depression
- ixekizumab(external link) for inflammatory conditions
- memantine hydrochloride(external link) for first line treatment of dementia
- memantine hydrochloride(external link) for second line treatment of dementia
- netupitant/palonosetron(external link) to preven nausea and vomiting associated with use of anti-cancer treatments
- influenza vaccine (high dose)(external link)for the prevention of influenza for some people aged 60 or over
- influenza vaccine (cell based)(external link) for the prevention of influenza
- pneumococcal conjugate vaccine (PCV15)(external link) for the prevention of invasive pneumococcal disease
- posaconazole(external link) for prevention of fungal infections in patients with acute lymphoblastic leukaemia
- posaconazole(external link) for prevention of fungal infections in patients with aplastic anaemia
- sacituzumab govitecan(external link) for a type of breast cancer
- trastuzumab(external link)for a type of breast cancer after disease progression