Imipramine (Tofranil) tablets 25 mg: Supply issue

Supply issue Active

AFT, the supplier of imipramine hydrochloride Tab 25 mg (Tofranil) has advised its New Zealand stock will expire at the end of November and the next shipment is delayed until mid-December.

Affected product

  • Chemical: Imipramine hydrochloride
  • Presentation: Tab 25 mg
  • Brand: Tofranil
  • Pharmacode: 2015250

Schedule listing for imipramine(external link)

There is no shortage of the 10 mg strength of imipramine hydrochloride tablets.

Alternative product

At this stage no suitable alternative brands have been located, Pharmac and AFT are continuing to explore options. 

We have received advice from our Mental Health Subcommittee (one of our expert clinical advisory groups). They advise that 2 x imipramine hydrochloride 10 mg tablets could be used as a temporary alternative.

The supplier, AFT Pharmaceuticals, advises that they have enough supply of imipramine hydrochloride 10 mg tablets to manage an increase in demand if it were used by all patients who usually use the imipramine hydrochloride 25 mg.

Who to contact

If you are a prescriber or pharmacist with questions about thissupply issue:

If you take imipramine hydrochloride (Tofranil) 25 mg tablets, talk to a health professional you trust. Pharmac cannot give clinical advice to individuals.

If you need to talk:

  • call or text 1737 any time (it’s free)
  • talk to a trained counsellor on the Depression helpline, 0800 111 757