NPPA outcome data
Summary of application results for 2019
| Outcome | Number of applications |
|---|---|
| Approved | 356 |
| Declined | 2 |
| Principles not met | 430 |
| Withdrawn application | 101 |
| Grand Total | 889 |
Download the data as a spreadsheet (includes medicines, outcomes and some indications)
- 2019 NPPA Website Data [XLSX 34 KB]
Note: We have excluded information about some applications for privacy reasons. Call the team if you have any questions about your particular medicine.
Outcomes of applications by medicine 2019
There is a breakdown by indication for each of the medicines in bold in the Excel spreadsheet download.
| Medicine | Approved | Declined | Principles not met | Withdrawn application | Grand Total |
|---|---|---|---|---|---|
| 4 aminopyridine | 1 | 1 | |||
| 40% glucose gel (Glucogel) | 1 | 1 | |||
| abiraterone | 1 | 1 | |||
| adalimumab | 2 | 6 | 8 | ||
| aflibercept | 2 | 1 | 3 | ||
| albendazole | 1 | 1 | 2 | ||
| alectinib | 1 | 1 | |||
| alpha tocopheryl acetate | 5 | 2 | 7 | ||
| alteplase | 1 | 1 | |||
| amikacin | 1 | 1 | |||
| amiloride | 3 | 3 | 4 | 10 | |
| amphotericin b | 1 | 1 | |||
| anakinra | 5 | 2 | 3 | 10 | |
| apixaban | 2 | 2 | |||
| aprepitant | 1 | 1 | 2 | ||
| aripiprazole | 5 | 5 | |||
| asparaginase (Crisantaspase) | 3 | 3 | |||
| atomoxetine | 1 | 1 | |||
| atp support (Bioceuticals) | 1 | 1 | |||
| axitinib | 1 | 1 | |||
| azacitidine | 6 | 2 | 1 | 9 | |
| bacillus calmette-guerin vaccine | 1 | 1 | |||
| basiliximab | 1 | 1 | |||
| bedaquiline | 9 | 1 | 10 | ||
| belinostat | 1 | 1 | |||
| bendamustine | 1 | 1 | |||
| bevacizumab | 6 | 1 | 7 | ||
| bortezomib | 6 | 6 | |||
| botulinum toxin type b | 2 | 2 | |||
| brentuximab | 1 | 3 | 4 | ||
| brimonidine (Alphagan P) | 1 | 2 | 3 | ||
| budesonide | 2 | 2 | |||
| buprenorphine | 1 | 1 | |||
| calcitonin | 1 | 1 | |||
| candesartan | 1 | 1 | |||
| cannabidiol | 1 | 1 | |||
| cannabidiol (Sativex) | 1 | 1 | |||
| cannabidiol (Tilray) | 8 | 8 | |||
| capsaicin | 1 | 1 | |||
| captopril | 1 | 1 | |||
| carbidopa / levodopa (Sinemet) | 1 | 1 | |||
| ceftolozane-tazobactam | 2 | 2 | |||
| cefuroxime | 1 | 1 | |||
| chlorhexidine | 1 | 1 | 2 | ||
| chlorvescent | 1 | 1 | |||
| cholestyramine | 2 | 2 | |||
| cimetidine | 1 | 1 | |||
| cinacalcet | 8 | 8 | |||
| cincalcet | 1 | 1 | |||
| citalopram | 1 | 1 | |||
| coenzyme q10 | 3 | 3 | |||
| colesevelam | 1 | 3 | 4 | ||
| collagenase clostridium histolyticum | 1 | 1 | |||
| continuous glucose monitor | 2 | 11 | 13 | ||
| creatine | 1 | 1 | |||
| cyclosporin | 26 | 26 | |||
| dabrafenib | 2 | 3 | 5 | ||
| daratumumab | 71 | 1 | 72 | ||
| deferasirox | 3 | 1 | 4 | ||
| deferiprone | 2 | 1 | 3 | ||
| deflazacort | 1 | 1 | |||
| delamanid | 1 | 1 | |||
| demeclocycline | 1 | 1 | 1 | 3 | |
| denosumab | 2 | 3 | 5 | ||
| desvenlafaxine | 1 | 1 | |||
| dexamethasone | 5 | 5 | |||
| dexrazoxane | 1 | 1 | |||
| dienogest | 1 | 1 | |||
| diethylcarbamazine | 1 | 1 | |||
| diloxanide | 1 | 1 | |||
| dipyridamole | 3 | 3 | |||
| dornase alfa | 2 | 2 | |||
| droxidopa | 1 | 1 | |||
| duloxetine | 3 | 1 | 4 | ||
| dupilumab | 2 | 2 | |||
| dutasteride | 1 | 1 | |||
| eculizumab | 1 | 1 | |||
| elecare powder | 1 | 1 | |||
| eltrombopag | 3 | 4 | 3 | 10 | |
| enoxaparin | 6 | 3 | 2 | 11 | |
| enzalutamide | 1 | 1 | |||
| eplerenone | 1 | 1 | |||
| erenumab | 1 | 1 | |||
| erlotinib | 3 | 3 | |||
| escitalopram (Airflow) | 1 | 1 | |||
| escitalopram (Lexapro) | 1 | 1 | |||
| escitalopram (Mylan) | 1 | 1 | |||
| estradiol | 1 | 1 | |||
| etanercept | 4 | 1 | 5 | ||
| everolimus | 1 | 1 | 4 | 6 | |
| evolocumab | 1 | 1 | |||
| exenatide | 1 | 1 | |||
| ezetimibe | 1 | 1 | |||
| famotidine | 4 | 4 | |||
| felbamate | 1 | 1 | |||
| ferric carboxymaltose | 2 | 2 | |||
| filgrastim | 1 | 1 | |||
| flash glucose monitoring system | 6 | 6 | |||
| flucytosine | 1 | 1 | |||
| folinic acid | 1 | 1 | |||
| fondaparinux | 1 | 1 | |||
| food thickener | 3 | 3 | |||
| formula (Energivit) | 1 | 1 | |||
| formula (Locasol) | 2 | 2 | |||
| formula (Neocate junior) | 1 | 1 | |||
| fortijuice | 1 | 1 | |||
| fortisip | 2 | 1 | 3 | ||
| fosaprepitant | 1 | 1 | |||
| fosfomycin | 1 | 1 | |||
| gabapentin (Neurontin) | 1 | 1 | |||
| gabapentin (Nupentin) | 1 | 1 | |||
| ganciclovir | 2 | 2 | |||
| gemcitabine | 1 | 1 | |||
| gentamicin | 1 | 1 | |||
| gilteritinib | 1 | 1 | |||
| glycine | 1 | 1 | |||
| glycopyrrolate | 1 | 1 | |||
| glycosade | 1 | 1 | |||
| guanfacine | 1 | 1 | |||
| hexamine hippurate | 1 | 1 | |||
| human papillomavirus vaccine | 1 | 1 | |||
| hydroxocobalamin | 2 | 2 | |||
| ibrutinib | 1 | 6 | 1 | 8 | |
| idebenone | 1 | 1 | |||
| indomethacin | 6 | 2 | 8 | ||
| infliximab | 5 | 3 | 8 | ||
| insulin detemir | 2 | 1 | 3 | ||
| ipilimumab | 1 | 1 | 2 | ||
| isonizid | 1 | 1 | |||
| itraconazole | 1 | 1 | |||
| ivabradine | 5 | 5 | |||
| ivacaftor | 1 | 1 | |||
| ketamine | 7 | 1 | 8 | ||
| ketoconazole | 1 | 1 | |||
| ketotifen | 1 | 1 | |||
| lanreotide | 1 | 1 | |||
| l-arginine | 3 | 3 | |||
| larotrectinib | 1 | 1 | |||
| latanoprost | 1 | 1 | |||
| l-carnitine | 3 | 3 | |||
| lenalidomide | 3 | 3 | 2 | 8 | |
| leuprorelin | 1 | 1 | |||
| levofloxacin | 3 | 2 | 1 | 6 | |
| levonorgestrel | 4 | 3 | 7 | ||
| lidocaine with prilocaine | 2 | 2 | |||
| linezolid | 9 | 4 | 13 | ||
| liothyronine | 1 | 1 | |||
| liposomal doxorubicin | 2 | 1 | 3 | ||
| lisdexamfetamine | 1 | 1 | |||
| l-taurine | 5 | 5 | |||
| l-tyrosine | 1 | 1 | |||
| melatonin | 2 | 2 | |||
| memantine | 1 | 1 | |||
| mepolizumab | 5 | 5 | |||
| methotrexate (Methoblastin) | 1 | 1 | |||
| methyl prednisolone | 1 | 1 | |||
| methylphenidate | 2 | 2 | |||
| migalastat | 2 | 2 | |||
| mirabegron | 5 | 5 | |||
| mitotane | 2 | 2 | |||
| moxifloxacin | 3 | 1 | 1 | 5 | |
| multivitamin | 1 | 2 | 3 | ||
| mycophenolic acid | 1 | 1 | |||
| nab paclitaxel | 1 | 1 | |||
| naltrexone | 2 | 2 | |||
| nimodipine | 1 | 1 | |||
| nitazoxanide | 1 | 1 | |||
| nivolumab | 1 | 1 | |||
| nusinersen | 1 | 1 | |||
| ocrelizumab | 2 | 2 | |||
| octreotide | 1 | 2 | 3 | ||
| omalizumab | 1 | 1 | |||
| omeprazole | 1 | 1 | |||
| ondansetron | 1 | 1 | |||
| oseltamivir | 1 | 1 | |||
| osimertinib | 1 | 1 | |||
| oxandrolone | 1 | 1 | |||
| oxcarbazepine | 1 | 1 | |||
| palbociclib | 1 | 1 | |||
| palivizumab | 4 | 4 | |||
| paracetamol with codeine | 1 | 1 | |||
| paromomycin | 1 | 1 | |||
| pazopanib | 2 | 2 | |||
| peginterferon alpha-2a | 1 | 3 | 4 | ||
| pegvisomant | 1 | 1 | |||
| pegylated liposomal doxorubicin | 2 | 2 | |||
| pembrolizumab | 4 | 4 | |||
| pemetrexed | 1 | 1 | |||
| perampanel | 1 | 1 | |||
| pertuzumab | 1 | 1 | |||
| phentermine | 1 | 1 | |||
| picosalax | 1 | 1 | |||
| pimecrolimus | 1 | 1 | |||
| pipobroman | 2 | 2 | |||
| plasmalyte | 1 | 1 | |||
| plerixafor | 1 | 1 | |||
| pneumococcal (pcv13) polysaccharide conjugate vaccine | 1 | 2 | 3 | ||
| polidocanol | 1 | 1 | |||
| ponatinib | 1 | 1 | 2 | ||
| posaconazole | 5 | 1 | 1 | 7 | |
| potassium chloride | 1 | 1 | 2 | ||
| potassium citrate | 2 | 2 | |||
| prasugrel | 2 | 1 | 3 | ||
| prednisilone | 1 | 1 | |||
| pristinamycin | 14 | 14 | |||
| propranolol | 1 | 1 | |||
| pyrimethamine | 1 | 1 | |||
| quinagolide | 2 | 2 | |||
| quinidine | 1 | 1 | |||
| raltitrexed | 1 | 1 | |||
| reboxetine | 1 | 1 | |||
| recombinant follicle stimulating hormone | 1 | 1 | |||
| regorafenib | 1 | 1 | |||
| ribavirin | 1 | 1 | |||
| riboflavin | 3 | 1 | 4 | ||
| risperidone | 1 | 1 | |||
| rituximab | 38 | 26 | 8 | 72 | |
| rosuvastatin | 4 | 4 | |||
| rufinamide | 4 | 4 | |||
| ruxolitinib | 8 | 2 | 10 | ||
| sapropterin | 1 | 1 | |||
| sargramostim | 1 | 1 | |||
| secukinumab | 1 | 5 | 6 | ||
| sertraline | 1 | 1 | |||
| sevelamer | 1 | 1 | |||
| simethicone | 1 | 1 | |||
| sirolimus ointment | 7 | 7 | |||
| sirolimus oral | 16 | 1 | 17 | ||
| sitafloxacin | 1 | 1 | |||
| sodium benzoate | 1 | 1 | |||
| sodium chloride (eye drops) | 1 | 1 | |||
| sodium chloride (Slow Sodium) | 6 | 6 | |||
| sodium dl 3-hydroxybutyrate | 3 | 3 | |||
| sodium picosulfate (Picoprep) | 1 | 1 | |||
| sodium picosulfate, magnesium oxide, citric acid (Picosalax) | 1 | 1 | |||
| sofosbuvir/valpatasvir | 1 | 1 | 2 | ||
| solifenacin succinate (Vesicare) | 1 | 1 | |||
| somatropin | 1 | 1 | |||
| sorafenib | 1 | 1 | |||
| spiramycin | 1 | 1 | |||
| stanozolol | 1 | 1 | |||
| sunitinib | 3 | 3 | |||
| tacrolimus (Prograf XL) | 1 | 1 | 2 | ||
| tacrolimus ointment | 2 | 1 | 3 | ||
| tafamidis | 4 | 4 | |||
| tamoxifen | 1 | 1 | |||
| taurolidine and citrate solution (Taurolock) | 1 | 1 | |||
| temozolomide | 1 | 1 | |||
| teniposide | 1 | 1 | |||
| tenofovir alafenamide | 1 | 1 | 2 | ||
| teriparatide | 3 | 3 | |||
| thalidomide | 2 | 1 | 3 | ||
| tibolone | 2 | 2 | |||
| ticagrelor | 1 | 1 | |||
| tinidazole | 1 | 1 | |||
| tizanidine | 2 | 2 | |||
| tobramycin | 1 | 1 | |||
| tocilizumab | 8 | 4 | 1 | 13 | |
| tofacitinib | 5 | 5 | |||
| trametinib | 2 | 2 | |||
| tranexamic acid | 1 | 1 | |||
| trastuzumab | 3 | 3 | |||
| trazodone | 1 | 1 | |||
| treosulphan | 3 | 3 | |||
| trihexyphenidyl | 3 | 3 | |||
| ustekinumab | 4 | 4 | |||
| valganciclovir | 8 | 1 | 9 | ||
| varicella vaccine (Varilrix) | 1 | 1 | |||
| vedoluzimab | 1 | 1 | |||
| venetoclax | 1 | 1 | |||
| venlafaxine | 1 | 6 | 6 | 13 | |
| vismodegib | 3 | 3 | |||
| voriconazole | 4 | 4 | |||
| whole thyroid | 1 | 1 | |||
| zinc | 2 | 2 | |||
| zoledronic acid (Aclasta) | 2 | 2 | |||
| zonisamide | 3 | 2 | 5 | ||
| Grand Total | 356 | 2 | 430 | 101 | 889 |